Most guinea pigs stay in a cage with bedding, toys, ramps and a food bowl and water bowl or water bottle. Each area of the cage should be completely cleaned at least once a week. On a daily basis or every other day basis, you should pick the cage meaning use a cat litter scoop to pick out the wet spots and droppings. Replace bedding if needed or just sprinkle fresh bedding on the areas where wet bedding was removed. Check the water bottle multiple times a day to ensure it stays full. You can clean or rinse out the water bottle one to two times a week. The food bowl should be checked for cleanliness as well. Once a week empty the cage completely. Wipe it down. Fill it with new bedding. Wipe down the ramps and toys, food bowl and water bowl or water bottle. For more tips call your Omaha, NE veterinary clinic.